Biography

Assoc. Prof. Yuning Zhang is from the Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, Jilin University.

He received his BS (2008) from Xi’an Jiaotong University, MS (2011) from Uppsala University and PhD (2015) from Karolinska Institutet respectively. Then he worked as a postdoctoral fellow(2015-2019) and later as a researcher(2019-2021) at KTH Royal Institute of Technology. He has been an Associate Professor in the First Hospital, Jilin University since 2021.

His main research interest is in the designed synthesis and application of dendritic polymer materials in biomedical therapies. He has co-authored over 30 research papers including J. Am. Chem. Soc., Adv. Funct. Mater., Small, etc.; applied 1 PCT Patent; co-edited 1 book.

Education

2015  Ph.D., Medical Science, Institute of Environmental Medicine, Karolinska Institutet

2011 M.S., Applied Biotechnology, Biomedical Centre, Uppsala University

1989 B.S., Bioengineering, School of Life Science and Technology, Xi’an Jiaotong University

Positions

2021- Associate Professor, The First Hospital, Jilin University

2019-2021  Researcher, Department of Fibre and Polymer Technology, KTH Royal Institute of Technology

2015-2019  Postdoctoral Fellow, Department of Fibre and Polymer Technology, KTH Royal Institute of Technology

Research Interest

Designed synthesis and application of dendritic polymer materials

1. Synthesis: One-Pot synthesis of MOF

2. Formulation: development of dendritic nanogel

3. Applications: cancer treatment, anti-bacteria, etc

Selected Publications

Coauthored over 30 papers in international journals, including J. Am. Chem. Soc., Adv. Funct. Mater., Small, Chem. Mater., etc., 1 book.

Total citations: > 1600 - H-index = 18 (Web of Knowledge).

1. Novel Therapeutic Platform of Micelles and Nanogels from Dopa-Functionalized Triblock Copolymers

Zhang, Y. N.*; Olofsson, K.; Fan, Y. M.; Sánchez, C. C.; Andrén O. C. J.; Qin, L. G.; Fortuin, L.; Malmström, E.; Malkoch, M.*, Small, 2021, 17, 2007305. DOI: 10.1002/smll.202007305

2. Off-Stoichiometric Thiol-Ene Chemistry to Dendritic Nanogel Therapeutics

Zhang, Y. N.#; Andrén O. C. J.#; Nordström, R.; Fan, Y. M.; Malmsten, M.; Mongkhontreerat, S.; Malkoch

M.*, Advanced Functional Materials, 2019, 29, 1806693. DOI: 10.1002/adfm.201806693

3. One-pot Synthesis of Metal–Organic Frameworks with Encapsulated Target Molecules and Their Applications for Controlled Drug Delivery

Zheng, H. Q.# *; Zhang, Y. N.#; Liu, L. F.; Wan, W.; Guo, P.; Nyström, A. M. *; Zou, X. D.*, Journal of the American Chemical Society, 2016, 138, 962−968. DOI: 10.1021/jacs.5b11720

Projects

2023.02-present  Study on the mechanism and effect of nanogel induced immune tolerance by targeted delivery of donor antigens to thymus, Key Project of Organ Regeneration and Transplantation of the Ministry of Education, 0.5 million (RMB)

2017.12-2019.11  LDP Nanomedicines Assisted Combination Therapy Targeting Acute Lymphoblastic Leukemia, Postdoc Project of Barncancerfonden, 1.05 million (RMB)